LOT OF 6 Boxes Replens Long-Lasting Vaginal Moisturizer 14 Ct single-use applicator exp 6/24. Replens Long-Lasting Vaginal Moisturizer Embracing change shouldn’t mean accepting discomfort and dryness. Replens Long-Lasting Vaginal Moisturizer helps replenish internal vaginal moisture and provides long-lasting results, without the use of estrogen. It lasts up to three days, supplementing the body’s natural lubrication, so you can regain comfort and confidence.