SELLING CHEAP! HUGE DESTASH!! NEW! Fast Shipping Smoke Free Home Bundle & Save Palo Santo, a highly revered essential oil in South America, translates from Spanish as "holy wood" and is traditionally used to elevate the mind and purify the air. It comes from the same botanical family as frankincense and is often used in meditation for its inspiring aroma that can evoke positive influences. Palo Santo can be diffused at home during the rainy season or used outdoors to keep unwanted annoyances at bay.