Brand New Unopened package. Retails $49 Zanfel™ is a safe and effective wash for urushiol-induced contact dermatitis. Urushiol is the toxin known to cause the itching and rash associated with poison ivy, oak, sumac, poisonwood, and related plants. Zanfel works by surrounding urushiol and bonding with it, thereby enabling it to be rinsed away. Unlike some products that require use within 10-20 minutes of contact or that require continued use until the rash is gone (which can take up to 5 weeks), Zanfel offers relief at any stage of the reaction and often with only one wash. Individuals with particularly severe reactions may require additional washes. Most individuals experience relief from the itching within 30 seconds of application. The rash will begin to subside within hours if the reaction is mild to moderate.